Head of the Department:  LTC doc. MUDr. Jan ÖSTERREICHER, Ph.D., tel.: +420-973 253 219, osterreicher@pmfhk.cz

 

Educational and Research Staff
ŠINKOROVÁ Zuzana
TICHÝ Aleš
ÖSTERREICHER Jan

VÁVROVÁ Jiřina

ZÁRYBNICKÁ Lenka

Technicians
MERVARTOVÁ Lenka
PRŮCHOVÁ Šárka
TÓTHOVÁ Iveta

The Department of Radiobiology was established at Purkyně Military Medical Research and Postgraduate Institute on 1 september 1963. The first chief of the department became Colonel Prof. MUDr. Josef Mráz, CSc., who was in 1968 appointed the first professor of military radiobiology of the Charles University. The main tasks of the department are teaching  and research activities which are closely connected.

In the field of research, the experimental work includes histology and cytology, in vitro method, methods of proteomic analysis and of methods flow cytometry. Individual technological units allow in vitro and in vivo observation of post-radiation mechanisms on molecular, cellular and organ levels.

Military research focused on early diagnosis and therapy of post-radiation damage in the main objective of the department. The aim of investigation in the medium-term horizon is discovery and practical introduction of bio-dosimetric markers as well as repeated renewal of decontamination agents pro the army. Mutual cooperation with other NBC research workplaces also remains an unseparable part of department research activities. Cooperation with civilian work places at the  Faculty  of  Medicine and the University Hospital in Hradec Králové is focused on radiation oncology.

Radiobiology takes part in military medical-specialist education in form of pre-gradual and post-gradual education mainly in doctoral studies. The main educational activity in military radiobiology  was to give lectures  about the nuclear weapons effects on living organism and the possibilities of the protection and treatment of irradiated persons. Many special military subjects such as disaster medicine and NBC protection  etc. which are taught at the Faculty of  Military Health Sciences, include topics which are presented by the instructors of the department.

Research Projects

Biological indicators of ionizing radiation
Řeháková, Z., Österreicher, J., Vilasová, Z., Pejchal, J., Tóthová, I., Tichý, A.
INDIKÁTORY II – Reverse detection of received ionizing radiation dose by monitoring of cell population changes using biophysical methods
Šinkorová, Z., Österreicher, J., Kročová, Z., Pejchal, J., Zárybnická, L., Tóthová, I.
New biological methods of the received dose determination
Šinkorová, Z., Faldyna, M., Zárybnická, L., Tichý, A., Vilasová, Z., Matiasovic, J.
RADSPEC – Short-term and long-term nonspecific changes in organisms exposed to high and low doses of nerve agents on cellular and molecular level
Österreicher, J.
RONSDOZ - Noninvasive measurement of proinflamatory markers of oxidative stress in irradiated as an indicator of received dose of radiation. Protective role of acetyl-L-carnitine
Vávrová, J., Österreicher, J., Tichý, A., Pejchal, J., Řezáčová, M.
Study of factors in a tissue microenviroment that influence the process of skeletal muscle reparation
Filip, S., Vávrová, J., Mokrý, J., Šinkorová, Z., Čížková, D., Tichý, A., Řezáčová, M.